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Structure of 213670-35-0
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Methyl 2,3-dioxo-2,3-dihydro-1H-indole-6-carboxylate features a fused indole core with adjacent diketone functionality and a methyl ester at the C6 position. This electron-deficient scaffold enables direct coupling in transition-metal-catalyzed reactions and serves as a key building block for heterocyclic libraries. The molecule exhibits enhanced stability under standard bench conditions and integrates readily into synthetic sequences requiring precise regiocontrol.
Methyl 2,3-dioxo-2,3-dihydro-1H-indole-6-carboxylate serves as a versatile building block for the synthesis of indole-based heterocycles and bioactive scaffolds. Its diketone functionality enables efficient cyclization and functionalization reactions, particularly in transition-metal-catalyzed couplings and condensation processes. The methyl ester group provides a handle for selective transformations, while the planar, electron-deficient core enhances reactivity in nucleophilic additions. Bench-stable and readily purified by chromatography, it functions effectively in both academic and industrial synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: