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Structure of 2136287-66-4
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7,8-Difluorodibenzo[b,e]thiepin-11(6H)-one features a rigid, electron-deficient aromatic core with strategically positioned fluorine atoms enhancing metabolic stability and membrane permeability. This scaffold integrates readily into bioactive molecule design, offering improved binding affinity in target-directed synthesis.
7,8-Difluorodibenzo[b,e]thiepin-11(6H)-one serves as a versatile fluorinated heterocyclic building block for medicinal chemistry campaigns. Its rigid, planar scaffold offers enhanced metabolic stability and modulates electronic properties through strategic fluorination. The ketone functionality enables direct derivatization via nucleophilic addition or reductive amination, while the difluoro substitution pattern supports favorable binding interactions in target-directed synthesis. Bench-stable and compatible with standard purification methods, it facilitates efficient access to complex molecular architectures in drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: