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CS-W001157 4
Total: USD 88.00

EPhos Pd G4

  • CAS No. 2132978-44-8

  • Cat. No. CS-0181545
  • Molecule weight918.55
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

EPhos Pd G4|CS-0181545

Structure of 2132978-44-8

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General Information

  • CAS No. 2132978-44-8
  • Cat. No. CS-0181545
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅₀H₇₀NO₄PPdS
  • Molecular Weight 918.55
  • Synonym(s) Methanesulfonato{Dicyclohexyl[3-(1-methylethoxy)-2',4',6'-tris(1-methylethyl)-1,1'-biphenyl-2-yl]phosphine}(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II)(Ephos Pd G4)
  • SMILES C[NH]1C(C=CC=C2)=C2C(C=CC=C3)=C3[Pd]([P](C4CCCCC4)(C5CCCCC5)C6=C(OC(C)C)C=CC=C6C7=C(C(C)C)C=C(C(C)C)C=C7C(C)C)1OS(C)(=O)=O

Application

EPhos Pd G4 serves as a highly efficient palladium catalyst for cross-coupling reactions, enabling robust C–C and C–heteroatom bond formation under mild conditions. Its electron-rich phosphine ligand enhances reactivity with challenging substrates, including sterically hindered and electron-deficient partners. The complex exhibits excellent stability, simplifies purification, and is well-suited for scalable synthesis in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.84
  • LogP   12.869
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   12

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