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Structure of 213190-12-6
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4-Bromo-2-fluoro-N-methylaniline features a strategically positioned bromo and fluoro substituent on an aniline scaffold, enabling selective coupling reactions in medicinal chemistry. The N-methyl group enhances metabolic stability and modulates electronic properties, while the ortho-fluoro effect directs regioselective functionalization. This bench-stable compound serves as a key building block for bioactive heterocycles and advanced pharmaceutical intermediates.
4-Bromo-2-fluoro-N-methylaniline serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds via palladium-catalyzed cross-coupling reactions. Its ortho-fluoro and para-bromo substituents provide complementary reactivity for sequential functionalization, while the N-methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and is compatible with standard reaction conditions, facilitating efficient access to complex heterocyclic systems and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: