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CS-W001157 4
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4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid

  • CAS No. 2130-56-5

  • Cat. No. CS-0360211
  • Molecule weight272.26
  • Purity≥98%
  • MDL No.MFCD00045837

*For research and further manufacturing use only, not for direct human use.

4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid|CS-0360211

Structure of 2130-56-5

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General Information

  • CAS No. 2130-56-5
  • Cat. No. CS-0360211
  • Purity ≥98%
  • MDL No. MFCD00045837
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂N₂O₄
  • Molecular Weight 272.26
  • Synonym(s) Benzidine-3,3'-dicarboxylic acid
  • SMILES O=C(O)C=1C=C(C=CC1N)C2=CC=C(N)C(=C2)C(=O)O

Description

This biphenyl-based diacid diamine features two amino groups flanked by carboxylic acid functionalities, enabling robust conjugation in polyamide and covalent network synthesis. The ortho-carboxylate positioning enhances solubility and facilitates modular assembly in advanced materials and bioconjugation platforms.

Application

4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid serves as a versatile building block for the synthesis of functionalized biphenyl scaffolds in medicinal chemistry and materials science. Its two amino groups enable facile coupling reactions, while the carboxylic acid functionalities offer opportunities for amide bond formation or salt engineering. The molecule exhibits good bench stability and facilitates purification via recrystallization, supporting its use in multi-step syntheses requiring high purity and predictable reactivity.

Synthesis

  • Route1

    References

    • Loewenherz Chemische Berichte, 1892 , vol. 25, p. 2797
  • Route2
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      573-79-5
    • ~%
    • In-stock
      4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid|CS-0360211
      2130-56-5

    References

    • Griess Chemische Berichte, 1874 , vol. 7, p. 1611
  • Route3
    • In-stock
      2-Nitrobenzoic acid|CS-W020072
      552-16-9
    • ~%
    • In-stock
      4,4'-Diamino-[1,1'-biphenyl]-3,3'-dicarboxylic acid|CS-0360211
      2130-56-5
    • null|null
      573-79-5

    References

    • Loeb Zeitschrift fuer Elektrochemie und Angewandte Physikalische Chemie, 1895 , vol. 2, p. 533 Chem. Zentralbl., 1896 , vol. 67, # I p. 902

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   126.64
  • LogP   1.9144
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   3

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