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CS-W001157 4
Total: USD 88.00

3-(Diphenylphosphino)benzoic acid

  • CAS No. 2129-30-8

  • Cat. No. CS-0699174
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Diphenylphosphino)benzoic acid|CS-0699174

Structure of 2129-30-8

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General Information

  • CAS No. 2129-30-8
  • Cat. No. CS-0699174
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₅O₂P
  • Molecular Weight 306.29
  • Synonym(s) None
  • SMILES OC(=O)C1=CC=CC(=C1)P(C1=CC=CC=C1)C1=CC=CC=C1

Description

This diphenylphosphino-substituted benzoic acid features a strategically positioned phosphine group that enhances metal coordination, enabling efficient ligand integration in catalytic systems. The carboxylic acid functionality supports conjugation and derivatization, while the electron-rich phosphine improves reactivity in cross-coupling processes.

Application

3-(Diphenylphosphino)benzoic acid serves as a versatile bifunctional building block for transition-metal-catalyzed cross-coupling and ligand development. The carboxylic acid group enables direct derivatization via esterification or amide formation, while the diphenylphosphino moiety provides strong coordination to palladium and platinum centers. This dual functionality facilitates efficient synthesis of phosphine-containing heterocycles and functionalized biaryls, with excellent bench stability and straightforward purification by recrystallization or chromatography.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.143
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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