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CS-W001157 4
Total: USD 88.00

2-Amino-3-bromo-6-chloropyrazine

  • CAS No. 212779-21-0

  • Cat. No. CS-W003753
  • Purity≥97%
  • MDL No.MFCD11044158

*For research and further manufacturing use only, not for direct human use.

2-Amino-3-bromo-6-chloropyrazine|CS-W003753

Structure of 212779-21-0

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General Information

  • CAS No. 212779-21-0
  • Cat. No. CS-W003753
  • Purity ≥97%
  • MDL No. MFCD11044158
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃BrClN₃
  • Molecular Weight 208.44
  • Synonym(s) 3-bromo-6-chloropyrazin-2-amine
  • SMILES BrC(N=CC(Cl)=N1)=C1N

Description

Nalpha-Benzyloxycarbonyl-L-2,3-diaminopropionic acid is a important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins.

Application

2-Amino-3-bromo-6-chloropyrazine serves as a versatile building block for the synthesis of heterocyclic scaffolds in medicinal chemistry and agrochemical research. Its orthogonal halogen and amino functionalities enable selective cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig couplings, under standard catalytic conditions. The compound exhibits good bench stability and facilitates efficient functionalization for downstream derivatization in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.4747
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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