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Structure of 2127096-38-0
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This indole derivative features a trifluoroethyl group enhancing metabolic stability and a reactive iodo substituent enabling efficient cross-coupling. The electron-rich indol-4-amine core supports diverse functionalization, while the pendant amine facilitates conjugation or salt formation. Designed for medicinal chemistry applications requiring robustness under standard conditions.
2-Iodo-1-(2,2,2-trifluoroethyl)-1H-indol-4-amine serves as a versatile building block for the construction of functionalized indole scaffolds in medicinal chemistry. The iodide group enables palladium-catalyzed cross-coupling reactions, while the trifluoroethyl moiety enhances metabolic stability and modulates lipophilicity. This compound exhibits good bench stability and facilitates efficient incorporation into complex molecular architectures via standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: