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CS-W001157 4
Total: USD 88.00

1,2-Bis(5-nitropyridin-2-yl)disulfane

  • CAS No. 2127-10-8

  • Cat. No. CS-W009923
  • Purity≥96%
  • MDL No.MFCD00006453

*For research and further manufacturing use only, not for direct human use.

1,2-Bis(5-nitropyridin-2-yl)disulfane|CS-W009923

Structure of 2127-10-8

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General Information

  • CAS No. 2127-10-8
  • Cat. No. CS-W009923
  • Purity ≥96%
  • MDL No. MFCD00006453
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆N₄O₄S₂
  • Molecular Weight None
  • Synonym(s) 2,2'-Dithiobis(5-nitropyridine)
  • SMILES [O-][N+](C1=CN=C(SSC2=NC=C([N+]([O-])=O)C=C2)C=C1)=O

Description

2,2-Dithiobis(5-nitropyridine) is an aromatic disulphide.2,2-Dithiobis(5-nitropyridine) was employed:as cysteine-activating reagent to study the NMR of G protein-coupled receptors in the deprotection assays for protected selenocysteine-containing peptidesfor deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cysteine and selenocysteineto remove the p-methoxybenzyl protecting group from cysteine and selenocysteine side-chains

Synthesis

  • Route1

    References

    • Journal of Medicinal Chemistry, , vol. 23, # 12 p. 1376 - 1380
  • Route2

    References

    • Justus Liebigs Annalen der Chemie, , vol. 487, p. 105,115
  • Route3

    References

    • Justus Liebigs Annalen der Chemie, , vol. 487, p. 105,115

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   112.06
  • LogP   3.0924
  • H_Acceptors   8
  • H_Donors   0
  • Rotatable_Bonds   5

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