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Structure of 2127-09-5
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5-Nitropyridine-2(1H)-thione features a conjugated heterocyclic core bearing both electron-deficient nitro and thione functionalities. This arrangement enables direct participation in transition metal-catalyzed cross-coupling reactions and facilitates coordination to metals in catalytic systems. The compound exhibits enhanced stability under standard bench conditions and displays favorable solubility in polar organic solvents for synthetic applications.
5-Nitropyridine-2(1H)-thione serves as a versatile building block in heterocyclic synthesis, enabling efficient access to functionalized pyridine derivatives. Its dual nitro and thione functionalities facilitate nucleophilic substitution, metal-catalyzed coupling, and cyclization reactions under mild conditions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it valuable for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: