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CS-W001157 4
Total: USD 88.00

2-(4-(Aminomethyl)piperidin-1-yl)ethanol

  • CAS No. 21168-72-9

  • Cat. No. CS-0155236
  • Molecule weight158.25
  • Purity≥97%
  • MDL No.MFCD06637707

*For research and further manufacturing use only, not for direct human use.

2-(4-(Aminomethyl)piperidin-1-yl)ethanol|CS-0155236

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General Information

  • CAS No. 21168-72-9
  • Cat. No. CS-0155236
  • Purity ≥97%
  • MDL No. MFCD06637707
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈N₂O
  • Molecular Weight 158.25
  • Synonym(s) None
  • SMILES OCCN1CCC(CN)CC1

Description

This piperidine-based ethanol derivative features a primary amine-functionalized side chain, enabling facile conjugation and solubility enhancement. The aminomethylpiperidine moiety imparts strong basic character and structural rigidity, ideal for medicinal chemistry scaffolds. Its bench-stable, moisture-tolerant profile supports reliable handling in synthesis workflows.

Application

2-(4-(Aminomethyl)piperidin-1-yl)ethanol serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient conjugation via its primary amine and hydroxyl groups. The piperidine scaffold provides favorable solubility and metabolic stability, while the pendant ethylene glycol linker enhances polarity and facilitates downstream derivatization. This compound functions reliably in standard amide coupling, reductive amination, and macrocyclization protocols, offering robust performance in both lead optimization and API intermediate synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.49
  • LogP   -0.3506
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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