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8-Bromo-11H-benzo[a]carbazole

  • CAS No. 21064-34-6

  • Cat. No. CS-0102885
  • Purity≥98%
  • MDL No.MFCD27644691

*For research and further manufacturing use only, not for direct human use.

8-Bromo-11H-benzo[a]carbazole|CS-0102885

Structure of 21064-34-6

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General Information

  • CAS No. 21064-34-6
  • Cat. No. CS-0102885
  • Purity ≥98%
  • MDL No. MFCD27644691
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₀BrN
  • Molecular Weight 296.16
  • Synonym(s) 8-bromo-11H-benzo[α]carbazole
  • SMILES BrC1=CC2=C(NC3=C2C=CC4=CC=CC=C34)C=C1

Description

8-Bromo-11H-benzo[a]carbazole features a brominated benzo[a]carbazole core with enhanced electron deficiency, enabling efficient coupling in cross-coupling reactions. This stable, crystalline compound integrates readily into functionalized heterocyclic scaffolds for materials science and pharmaceutical development.

Application

8-Bromo-11H-benzo[a]carbazole serves as a versatile building block for the synthesis of carbazole-based scaffolds in medicinal chemistry and materials science. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, facilitating efficient access to functionalized derivatives. The compound exhibits good bench stability, ease of purification, and compatibility with diverse reaction conditions, making it well-suited for iterative synthetic strategies targeting biologically active heterocycles and optoelectronic materials.

Synthesis

  • Route1
    • null|null
      50823-80-8
    • ~96%
    • In-stock
      8-Bromo-11H-benzo[a]carbazole|CS-0102885
      21064-34-6

    References

    • LG Chem, Ltd. Patent: EP2332911 A2, 2011 ; Location in patent: Page/Page column 33 ;
  • Route2

    References

    • Buu-Hoi et al. Recueil des Travaux Chimiques des Pays-Bas, 1950 , vol. 69, p. 1053,1078
  • Route3

    References

    • LG Chem, Ltd. Patent: EP2332911 A2, 2011 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   5.2368
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   0

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