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Structure of 21010-06-0
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5-(Thiophen-2-yl)pentanoic acid features a thiophene ring tethered via a five-carbon aliphatic chain to a carboxylic acid group, enabling integration into bioactive molecules requiring aromatic-hydrophobic balance. The pendant thiophene imparts electron-rich character and planarity, enhancing π-stacking interactions in target binding. This structure supports applications in medicinal chemistry and materials science where controlled solubility and electronic properties are critical.
5-(Thiophen-2-yl)pentanoic acid serves as a versatile building block for the synthesis of bioactive molecules, particularly in medicinal chemistry and agrochemical research. Its thiophene-containing alkyl chain provides enhanced metabolic stability and favorable lipophilicity, enabling efficient incorporation into diverse scaffolds. The carboxylic acid functionality facilitates straightforward derivatization via amide, ester, or acyl chloride formation, supporting broad synthetic utility in peptide conjugation and macrocyclization strategies.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: