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CS-W001157 4
Total: USD 88.00

Thalidomide-O-PEG2-propargyl

  • CAS No. 2098487-52-4

  • Cat. No. CS-0104609
  • Purity≥98%
  • MDL No.MFCD32063462

*For research and further manufacturing use only, not for direct human use.

Thalidomide-O-PEG2-propargyl|CS-0104609

Structure of 2098487-52-4

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General Information

  • CAS No. 2098487-52-4
  • Cat. No. CS-0104609
  • Purity ≥98%
  • MDL No. MFCD32063462
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₀N₂O₇
  • Molecular Weight 400.38
  • Synonym(s) E3 ligase Ligand-Linker Conjugates 32
  • SMILES O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCOCCOCC#C)=O

Description

Thalidomide-O-PEG2-propargyl features a propargyl group appended via a two-ethylene glycol spacer to the hydroxyl moiety of thalidomide, enabling bioorthogonal conjugation. This derivative maintains the core pharmacophore while offering enhanced solubility and a reactive handle for click chemistry applications in targeted drug delivery and chemical biology studies.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   111.24
  • LogP   -0.1184
  • H_Acceptors   9
  • H_Donors   1
  • Rotatable_Bonds   9

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