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CS-W001157 4
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6-Bromo-1-methyl-1H-pyrrolo[3,2-c]pyridine

  • CAS No. 2091221-98-4

  • Cat. No. CS-0196987
  • Molecule weight211.06
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-1-methyl-1H-pyrrolo[3,2-c]pyridine|CS-0196987

Structure of 2091221-98-4

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General Information

  • CAS No. 2091221-98-4
  • Cat. No. CS-0196987
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrN₂
  • Molecular Weight 211.06
  • Synonym(s) None
  • SMILES CN1C=CC2=C1C=C(Br)N=C2

Description

6-Bromo-1-methyl-1H-pyrrolo[3,2-c]pyridine is a heterocyclic building block featuring a bromine substituent at the 6-position and a methyl group at the 1-position. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions, integrating efficiently into complex molecular architectures under standard conditions.

Application

6-Bromo-1-methyl-1H-pyrrolo[3,2-c]pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine electrophile and electron-rich pyrrolopyridine core. The methyl group enhances stability and modulates reactivity, while the heterocyclic scaffold is compatible with standard synthetic workflows, facilitating efficient access to biologically active compounds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   2.3358
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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