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Triphenyl(prop-2-yn-1-yl)phosphonium bromide

  • CAS No. 2091-46-5

  • Cat. No. CS-0063207
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Triphenyl(prop-2-yn-1-yl)phosphonium bromide|CS-0063207

Structure of 2091-46-5

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General Information

  • CAS No. 2091-46-5
  • Cat. No. CS-0063207
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₈BrP
  • Molecular Weight 381.25
  • Synonym(s) Triphenylpropargylphosphonium bromide
  • SMILES C#CC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Description

Triphenyl(prop-2-yn-1-yl)phosphonium bromide delivers a stable, bench-ready phosphonium salt featuring a terminal alkyne group. This reagent enables efficient copper-free Sonogashira couplings and facilitates the incorporation of alkyne handles into complex molecular architectures. The propargylic linkage provides high reactivity in cross-coupling protocols while maintaining compatibility with sensitive functional groups.

Synthesis

  • Route1
    • null|null
      106-96-7
    • null|null
      603-35-0
    • ~77%
    • In-stock
      Triphenyl(prop-2-yn-1-yl)phosphonium bromide|CS-0063207
      2091-46-5

    References

    • Bagdasaryan; Pogosyan; Panosyan; Indzhikyan Russian Journal of General Chemistry, 2008 , vol. 78, # 6 p. 1177 - 1183

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   0.6177
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   4

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