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Structure of 208709-55-1
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trans-2,3-Difluorobutylcyclohexylbenzene features a rigid cyclohexyl spacer flanked by electron-withdrawing fluorine atoms, delivering enhanced metabolic stability and lipophilic character. This structural motif enables precise tuning of membrane permeability and target engagement in bioactive molecule design.
trans-2,3-Difluorobutylcyclohexylbenzene serves as a versatile building block for fluorinated aromatic scaffolds in medicinal chemistry. Its trans-difluoro substitution pattern enhances metabolic stability and modulates lipophilicity, while the 4-propylcyclohexyl ether moiety provides conformational rigidity and favorable pharmacokinetic properties. The compound exhibits excellent bench stability, tolerates diverse reaction conditions, and facilitates efficient functionalization in standard coupling protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: