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CS-W001157 4
Total: USD 88.00

2-Amino-3-(3-iodophenyl)propanoic acid

  • CAS No. 20846-38-2

  • Cat. No. CS-0156898
  • Purity≥95%
  • MDL No.MFCD05227974

*For research and further manufacturing use only, not for direct human use.

2-Amino-3-(3-iodophenyl)propanoic acid|CS-0156898

Structure of 20846-38-2

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General Information

  • CAS No. 20846-38-2
  • Cat. No. CS-0156898
  • Purity ≥95%
  • MDL No. MFCD05227974
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀INO₂
  • Molecular Weight 291.09
  • Synonym(s) m-Iodophenylalanine
  • SMILES C1=CC(=CC(=C1)I)CC(C(=O)O)N

Description

2-Amino-3-(3-iodophenyl)propanoic acid features a para-iodinated phenyl moiety that enhances its utility in transition-metal-catalyzed cross-coupling reactions. This bench-stable amino acid derivative integrates readily into peptide scaffolds and serves as a key building block for bioconjugation and medicinal chemistry applications.

Application

2-Amino-3-(3-iodophenyl)propanoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its iodophenyl group enables palladium-catalyzed cross-coupling reactions, while the α-amino acid functionality offers compatibility with standard peptide coupling and derivatization protocols. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.2456
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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