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Structure of 20776-61-8
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2-Amino-4,5-dichlorobenzoic acid features a sterically hindered aromatic core with dual electron-withdrawing chlorine substituents flanking a nucleophilic amino group. This combination enables direct coupling reactions under mild conditions, delivering robust intermediates for pharmaceutical and agrochemical synthesis. The carboxylic acid moiety facilitates salt formation and solubility tuning in polar solvents.
2-Amino-4,5-dichlorobenzoic acid serves as a versatile building block for heterocyclic synthesis and medicinal chemistry campaigns. Its ortho-amino and carboxylic acid functionalities enable direct coupling reactions and cyclization pathways under standard conditions. The molecule exhibits good bench stability and facilitates efficient purification via crystallization or ion-exchange chromatography. Functions as a key intermediate in the construction of bioactive scaffolds requiring halogenated aromatic cores with tunable nitrogen functionality.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: