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Structure of 20754-22-7
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(E)-Methyl 3-(4-(trifluoromethyl)phenyl)acrylate features a conjugated enoate system with a para-trifluoromethyl aryl group, delivering enhanced electron-withdrawing character and improved stability under standard conditions. This structural motif enables efficient incorporation into Michael additions and Diels-Alder reactions, serving as a robust building block for functionalized heterocycles and advanced synthetic intermediates in medicinal chemistry workflows.
(E)-Methyl 3-(4-(trifluoromethyl)phenyl)acrylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to conjugated systems via standard Michael additions and Diels–Alder reactions. The (E)-configured enoate ester exhibits excellent bench stability and facilitates straightforward purification, while the electron-withdrawing trifluoromethyl group enhances reactivity in nucleophilic transformations. Its structural motif is commonly employed in the synthesis of functionalized heterocycles and bioactive scaffolds relevant to medicinal chemistry research.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: