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CS-W001157 4
Total: USD 88.00

4,4-Dimethylcyclohexanamine

  • CAS No. 20615-18-3

  • Cat. No. CS-0153791
  • Purity≥97%
  • MDL No.MFCD08460046

*For research and further manufacturing use only, not for direct human use.

4,4-Dimethylcyclohexanamine|CS-0153791

Structure of 20615-18-3

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General Information

  • CAS No. 20615-18-3
  • Cat. No. CS-0153791
  • Purity ≥97%
  • MDL No. MFCD08460046
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇N
  • Molecular Weight 127.23
  • Synonym(s) 4,4-DIMETHYLCYCLOHEXYLAMINE
  • SMILES CC1(C)CCC(CC1)N

Description

4,4-Dimethylcyclohexanamine features a sterically hindered amine group within a stable cyclohexane core, enhancing its resistance to over-alkylation. This bench-stable, moisture-tolerant amine integrates readily into synthetic routes requiring a bulky, electron-rich nitrogen donor.

Application

4,4-Dimethylcyclohexanamine serves as a versatile chiral building block in medicinal chemistry, offering enhanced lipophilicity and metabolic stability compared to unsubstituted cyclohexylamines. Its tertiary amine functionality facilitates salt formation and enables efficient derivatization via alkylation or acylation. The gem-dimethyl substitution provides steric shielding and improved bench stability, making it well-suited for use in API synthesis and catalyst development.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.9139
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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