1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one

Name: 1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2055839-77-3
Cat. No. CS-0052652
Purity≥97%
MDL No.MFCD30530452

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one|CS-0052652

Structure of 2055839-77-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 2055839-77-3
Cat. No. CS-0052652
Purity ≥97%
MDL No. MFCD30530452
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀O₂
Molecular Weight 126.15
Synonym(s) 1-(3-Hydroxybicyclo[1.1.1]pentan-1-yl)ethanone
SMILES CC(=O)C12CC(O)(C1)C2

Description

This bicyclic ketone features a rigid, strained 1.1.1-bicyclo[1.1.1]pentane scaffold with a pendant hydroxyl group, enabling unique steric and electronic properties. The molecule combines enhanced stability with high functional group tolerance, facilitating integration into complex synthetic sequences. Its distinctive topology supports applications in medicinal chemistry and molecular probe design.

Application

1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one serves as a versatile building block for strained bicyclic scaffolds, enabling efficient access to functionalized 3-hydroxybicyclo[1.1.1]pentane motifs. The ketone functionality facilitates downstream transformations including reduction, nucleophilic addition, and conjugate additions, while the rigid, sterically encumbered core enhances metabolic stability. Bench-stable and compatible with standard synthetic protocols, it supports rapid diversification in medicinal chemistry campaigns targeting CNS-active compounds and enzyme inhibitors.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.3
LogP 0.4904
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Skeleton Bridge Rings compounds Other bridge ring compounds

Building Blocks Skeleton Fatty ring compounds Cyclobutane compounds

Key Words

2055839-77-3 sigma2055839-77-3 manufacturer2055839-77-3 price2055839-77-3 structure2055839-77-3 SDSbuy 2055839-77-32055839-77-3 supplier2055839-77-3 uses2055839-77-3 molecular weightprice of 2055839-77-32055839-77-3 chemical name formula of 2055839-77-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-{3-Hydroxybicyclo[1.1.1]pentan-1-yl}ethan-1-one

CAS No. 2055839-77-3

Recommended Products