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Structure of 205114-17-6
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Methyl 3-bromoquinoline-6-carboxylate features a brominated quinoline core with a methyl ester at the C6 position, enabling direct functionalization in cross-coupling reactions. The electron-deficient aromatic system enhances reactivity in palladium-catalyzed transformations, while the ester group offers a handle for downstream derivatization. This bench-stable reagent integrates efficiently into synthetic sequences requiring halogenated heterocycles.
Methyl 3-bromoquinoline-6-carboxylate serves as a versatile building block for the synthesis of quinoline-based pharmaceuticals and agrochemicals. The bromine at the 3-position enables palladium-catalyzed cross-coupling reactions, while the ester group facilitates further functionalization via hydrolysis or reduction. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for iterative synthetic strategies in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: