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CS-W001157 4
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(3S)-3-Aminoazetidin-2-one hydrochloride

  • CAS No. 2044711-48-8

  • Cat. No. CS-0053270
  • Purity≥97%
  • MDL No.MFCD30530421

*For research and further manufacturing use only, not for direct human use.

(3S)-3-Aminoazetidin-2-one hydrochloride|CS-0053270

Structure of 2044711-48-8

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General Information

  • CAS No. 2044711-48-8
  • Cat. No. CS-0053270
  • Purity ≥97%
  • MDL No. MFCD30530421
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇ClN₂O
  • Molecular Weight 122.55
  • Synonym(s) None
  • SMILES Cl.N[C@H]1CNC1=O

Description

(3S)-3-Aminoazetidin-2-one hydrochloride features a chiral azetidinone core with a primary amine at the 3-position, offering enhanced solubility and stability under standard conditions. This bench-stable scaffold integrates readily into peptide-like architectures and serves as a key building block in bioactive molecule design.

Application

(3S)-3-Aminoazetidin-2-one hydrochloride serves as a key chiral building block in the synthesis of β-lactam-containing pharmaceuticals and bioactive heterocycles. Its stability, solubility, and functional group tolerance enable efficient incorporation into complex molecules via standard amine coupling and cyclization protocols. The compound facilitates the construction of strained azetidinone cores under mild conditions, supporting scalable and reproducible synthetic workflows for medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   -1.1347
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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