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CS-W001157 4
Total: USD 88.00

Tributyl(methyl)phosphonium dimethyl phosphate

  • CAS No. 20445-88-9

  • Cat. No. CS-0160297
  • Purity≥97%
  • MDL No.MFCD22377743

*For research and further manufacturing use only, not for direct human use.

Tributyl(methyl)phosphonium dimethyl phosphate|CS-0160297

Structure of 20445-88-9

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General Information

  • CAS No. 20445-88-9
  • Cat. No. CS-0160297
  • Purity ≥97%
  • MDL No. MFCD22377743
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₃₆O₄P₂
  • Molecular Weight 342.39
  • Synonym(s) )phosphonium dimethyL
  • SMILES C[P+](CCCC)(CCCC)CCCC.O=P(OC)([O-])OC

Description

Tributyl(methyl)phosphonium dimethyl phosphate serves as a stable, moisture-tolerant phosphonium reagent for efficient Wittig-type olefination. This compound integrates a methyl-substituted phosphonium center with a dimethyl phosphate counterion, enhancing solubility in polar aprotic solvents and enabling smooth reaction initiation under standard conditions.

Application

Tributyl(methyl)phosphonium dimethyl phosphate serves as a stable, bench-ready reagent for the Wittig-type olefination of aldehydes and ketones, enabling efficient synthesis of terminal and internal alkenes. Its phosphonium salt structure offers excellent functional group tolerance and ease of handling, with byproducts readily removed during standard aqueous workups. This reagent facilitates high-yielding transformations in complex molecule assembly, particularly valuable in the construction of conjugated systems and heterocyclic scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.59
  • LogP   4.7817
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   11

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