Fmoc-L-HTyr(tBu)-OH

Name: Fmoc-L-HTyr(tBu)-OH
Brand: ChemScene
Availability: InStock
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CAS No. 204384-69-0
Cat. No. CS-0087329
Purity≥97%
MDL No.MFCD01321420

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Description

Fmoc-L-HTyr(tBu)-OH is a protected tyrosine derivative featuring a fluorenylmethoxy carbonyl (Fmoc) group and a tert-butyl ether protecting group on the phenolic hydroxyl. This combination enables efficient incorporation into peptide chains under standard solid-phase synthesis conditions, offering excellent solubility and stability during coupling steps.

Application

Fmoc-L-HTyr(tBu)-OH serves as a key building block in peptide synthesis, enabling the incorporation of hydroxytyrosine with orthogonal protection. The Fmoc group allows for mild deprotection under basic conditions, while the tBu group on the phenolic hydroxyl ensures stability and selective deprotection. This derivative facilitates efficient coupling reactions and is compatible with standard solid-phase protocols, offering reliable access to bioactive peptides containing phosphorylated tyrosine analogs.

General Information

CAS No. 204384-69-0
Cat. No. CS-0087329
Purity ≥97%
MDL No. MFCD01321420
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₉H₃₁NO₅
Molecular Weight 473.56
Synonym(s) None
SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCC4=CC=C(OC(C)(C)C)C=C4

Computational Chemistry Data

TPSA 84.86
LogP 5.7884
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 8

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Tyrosine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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Fmoc-L-HTyr(tBu)-OH

CAS No. 204384-69-0

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