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CS-W001157 4
Total: USD 88.00

Fmoc-L-HTyr(tBu)-OH

  • CAS No. 204384-69-0

  • Cat. No. CS-0087329
  • Purity≥97%
  • MDL No.MFCD01321420

*For research and further manufacturing use only, not for direct human use.

Fmoc-L-HTyr(tBu)-OH|CS-0087329

Structure of 204384-69-0

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General Information

  • CAS No. 204384-69-0
  • Cat. No. CS-0087329
  • Purity ≥97%
  • MDL No. MFCD01321420
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₃₁NO₅
  • Molecular Weight 473.56
  • Synonym(s) None
  • SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCC4=CC=C(OC(C)(C)C)C=C4

Description

Fmoc-L-HTyr(tBu)-OH is a protected tyrosine derivative featuring a fluorenylmethoxy carbonyl (Fmoc) group and a tert-butyl ether protecting group on the phenolic hydroxyl. This combination enables efficient incorporation into peptide chains under standard solid-phase synthesis conditions, offering excellent solubility and stability during coupling steps.

Application

Fmoc-L-HTyr(tBu)-OH serves as a key building block in peptide synthesis, enabling the incorporation of hydroxytyrosine with orthogonal protection. The Fmoc group allows for mild deprotection under basic conditions, while the tBu group on the phenolic hydroxyl ensures stability and selective deprotection. This derivative facilitates efficient coupling reactions and is compatible with standard solid-phase protocols, offering reliable access to bioactive peptides containing phosphorylated tyrosine analogs.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   5.7884
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   8

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