(Tert-butoxycarbonyl)-L-serine hydrate

Name: (Tert-butoxycarbonyl)-L-serine hydrate
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CAS No. 204191-40-2
Cat. No. CS-0449492
Purity≥95%
MDL No.MFCD00150501

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(Tert-butoxycarbonyl)-L-serine hydrate|CS-0449492

Structure of 204191-40-2

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General Information

CAS No. 204191-40-2
Cat. No. CS-0449492
Purity ≥95%
MDL No. MFCD00150501
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₇NO₆
Molecular Weight 223.22
Synonym(s) Boc-L-Serine Hydrate
SMILES CC(OC(N[C@@H](CO)C(O)=O)=O)(C)C.O

Description

(Tert-butoxycarbonyl)-L-serine hydrate features a protected amino group and a hydroxyl-bearing side chain, enabling selective derivatization in peptide synthesis. This bench-stable, moisture-tolerant reagent integrates seamlessly into solid-phase workflows, delivering reliable coupling efficiency under standard conditions.

Application

(Tert-butoxycarbonyl)-L-serine hydrate serves as a stable, bench-ready amino acid derivative enabling efficient peptide synthesis. The Boc group provides orthogonal protection for the amine, while the serine side chain hydroxyl remains available for selective functionalization. Its crystalline form and ease of purification facilitate reliable handling in multistep syntheses, making it a practical building block for peptidomimetics and complex heterocyclic scaffolds.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 127.36
LogP -0.8681
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 3

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

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(Tert-butoxycarbonyl)-L-serine hydrate

CAS No. 204191-40-2

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