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Structure of 20409-48-7
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This thiophene-bearing ketone features a sterically hindered α-carbon, enhancing stability and facilitating selective transformations. The conjugated thiophenyl group imparts electronic delocalization, enabling efficient coupling in cross-coupling reactions and serving as a robust scaffold for synthetic intermediates in pharmaceutical and materials chemistry.
2,2-Dimethyl-1-(thiophen-2-yl)propan-1-one serves as a versatile building block in heterocyclic synthesis, enabling efficient construction of thiophene-fused scaffolds. Its α,α-dimethyl ketone functionality enhances bench stability and facilitates direct functionalization via enolization or nucleophilic addition. The molecule exhibits excellent compatibility with standard coupling protocols and functions as a key intermediate in the development of bioactive compounds, particularly those requiring sterically hindered aryl ketone motifs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H317
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: