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Structure of 203866-19-7
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This fluorenylmethoxy carbamate-protected pyrrolidine derivative features a stereodefined (2S,4S) configuration and a fluorinated C4 position, enhancing metabolic stability. The Fmoc group enables efficient solid-phase synthesis, while the carboxylic acid moiety serves as a direct coupling handle in peptide elongation workflows.
(2S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-fluoropyrrolidine-2-carboxylic acid serves as a stereochemically defined building block for the synthesis of fluorinated proline analogs. The Fmoc group provides orthogonal protection and facilitates purification via standard chromatographic methods. The 4-fluoro substituent enhances conformational rigidity and modulates electronic properties, enabling its use in peptide coupling reactions and the construction of bioactive heterocyclic scaffolds relevant to medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: