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CS-W001157 4
Total: USD 88.00

(2S,4S)-1-tert-Butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate

  • CAS No. 203866-16-4

  • Cat. No. CS-W001496
  • Purity≥95%
  • MDL No.MFCD11054130

*For research and further manufacturing use only, not for direct human use.

(2S,4S)-1-tert-Butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate|CS-W001496

Structure of 203866-16-4

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General Information

  • CAS No. 203866-16-4
  • Cat. No. CS-W001496
  • Purity ≥95%
  • MDL No. MFCD11054130
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₈FNO₄
  • Molecular Weight 247.26
  • Synonym(s) 1-tert-butyl 2-methyl (2S,4S)-4-fluoropyrrolidine-1,2-dicarboxylate
  • SMILES COC(=O)[C@@H]1C[C@@H](CN1C(=O)OC(C)(C)C)F

Synthesis

  • Route1

    References

    • SUNSHINE LAKE PHARMA CO.,LTD.; ZHANG, Jiancun; ZHANG, Yingjun; XIE, Hongming; REN, Qingyun; HU, Bailin; FU, Changping; WU, Xiwei; LI, Shifeng; WANG, Chenglin; ZHANG, Zhikeng Patent: WO2014/82379 A1, 2014 ; Location in patent: Page/Page column 144; 145 ;
  • Route2
    • null|null
      189160-59-6
    • ~70%
    • In-stock
      (2S,4S)-1-tert-Butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate|CS-W001496
      203866-16-4

    References

    • Kim, Dong Wook; Ahn, Doo-Sik; Oh, Young-Ho; Lee, Sungyul; Kil, Hee Seup; Oh, Seung Jun; Lee, Sang Ju; Kim, Jae Seung; Ryu, Jin Sook; Moon, Dae Hyuk; Chi, Dae Yoon Journal of the American Chemical Society, 2006 , vol. 128, # 50 p. 16394 - 16397
  • Route3
    • null|null
      189160-59-6
    • ~85%
    • In-stock
      1-(tert-Butyl) 2-methyl (S)-2,5-dihydro-1H-pyrrole-1,2-dicarboxylate|CS-0099904
      74844-93-2
    • In-stock
      (2S,4S)-1-tert-Butyl 2-methyl 4-fluoropyrrolidine-1,2-dicarboxylate|CS-W001496
      203866-16-4

    References

    • Journal of Organic Chemistry, , vol. 73, # 20 p. 8106 - 8108

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS09
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H401-H411
Precautionary Statements : P273-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.84
  • LogP   1.5069
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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