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Structure of 2036-41-1
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5-Methylpyrimidine features a methyl group at the pyrimidine ring's 5-position, enhancing electron density and altering reactivity compared to parent pyrimidine. This substitution improves stability under standard conditions and facilitates selective functionalization in synthetic pathways. The compound serves as a key scaffold in heterocyclic chemistry, particularly for medicinal chemistry applications requiring tunable electronic properties and metabolic resistance.
5-Methylpyrimidine serves as a versatile heterocyclic building block in medicinal chemistry and agrochemical synthesis. Its pyrimidine core provides a robust scaffold for functionalization at nitrogen and carbon positions, enabling access to diverse derivatives via electrophilic substitution or transition-metal-catalyzed coupling. The methyl group enhances metabolic stability and modulates electronic properties, contributing to improved pharmacokinetic profiles. This compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating efficient purification and integration into complex molecular architectures.
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H228-H302
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Precautionary Statements : P210-P240-P241-P264-P270-P280-P330-P370+P378-P501
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Lot numbers can be found on the outside label of a product: