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CS-W001157 4
Total: USD 88.00

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one

  • CAS No. 20348-09-8

  • Cat. No. CS-W002009
  • Purity≥98%
  • MDL No.MFCD00006697

*For research and further manufacturing use only, not for direct human use.

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one|CS-W002009

Structure of 20348-09-8

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General Information

  • CAS No. 20348-09-8
  • Cat. No. CS-W002009
  • Purity ≥98%
  • MDL No. MFCD00006697
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O₂
  • Molecular Weight 150.13
  • Synonym(s) 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one
  • SMILES O=C1NC2=NC=CC=C2OC1

Description

2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one was used in the synthesis of quinazolinbenzoxazine derivatives.

Application

2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused bicyclic structure exhibits robust bench stability and tolerates diverse functional groups, enabling efficient incorporation into complex molecular architectures. The core scaffold participates reliably in nucleophilic substitution and transition-metal-catalyzed coupling reactions, facilitating rapid access to analogs for structure-activity investigations.

Synthesis

  • Route1
    • null|null
      1268818-15-0
    • ~74%
    • In-stock
      2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one|CS-W002009
      20348-09-8

    References

    • Tetrahedron, , vol. 67, # 6 p. 1187 - 1192
  • Route2
    • In-stock
      2-Amino-3-hydroxypyridine|CS-W007794
      16867-03-1
    • null|null
      79-11-8
    • ~%
    • In-stock
      2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one|CS-W002009
      20348-09-8

    References

    • WO2004/14384 A2, ; Page/Page column 256; 262 ; WO 2004/014384 A2
  • Route3
    • In-stock
      2-Amino-3-hydroxypyridine|CS-W007794
      16867-03-1
    • null|null
      79-04-9
    • ~67%
    • In-stock
      2H-Pyrido[3,2-b][1,4]oxazin-3(4H)-one|CS-W002009
      20348-09-8

    References

    • Bioorganic and Medicinal Chemistry, , vol. 6, # 2 p. 133 - 142

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   51.22
  • LogP   0.4125
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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