2-Chloro-1-pyrrolidin-1-ylethanone

Name: 2-Chloro-1-pyrrolidin-1-ylethanone
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 20266-00-6
Cat. No. CS-0037280
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-1-pyrrolidin-1-ylethanone|CS-0037280

Structure of 20266-00-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 20266-00-6
Cat. No. CS-0037280
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₀ClNO
Molecular Weight 147.60
Synonym(s) Pyrrolidine, 1-(chloroacetyl)-
SMILES C1CCN(C1)C(=O)CCl

Description

1-(Chloroacetyl)pyrrolidine is a reactive acylating agent featuring a chloroacetyl group tethered to a pyrrolidine ring. This configuration enables selective functionalization of nucleophiles, particularly amines and thiols, under mild conditions. The molecule combines high reactivity with bench-stable handling, making it valuable for bioconjugation and synthetic intermediate applications.

Application

1-(Chloroacetyl)pyrrolidine serves as a versatile acylating agent in synthetic organic chemistry, enabling efficient introduction of chloroacetyl groups into nucleophilic substrates. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecules. The molecule functions effectively in the construction of heterocyclic scaffolds and bioactive intermediates, particularly in medicinal chemistry workflows requiring selective C-acylation or subsequent displacement reactions.

Synthesis

Route1
- 123-75-1
- 79-04-9
- ~99%
- In-stock
  
  20266-00-6
References
- Li, Yang; Zhang, Yu; Huang, Zhi; Cao, Xiaoping; Gao, Kun Canadian Journal of Chemistry, 2004 , vol. 82, # 5 p. 622 - 630
Route2
- 616-45-5
- 79-11-8
- ~87%
- In-stock
  
  20266-00-6
References
- Youngsaye, Willmen; Dockendorff, Chris; Vincent, Benjamin; Hartland, Cathy L.; Bittker, Joshua A.; Dandapani, Sivaraman; Palmer, Michelle; Whitesell, Luke; Lindquist, Susan; Schreiber, Stuart L.; Munoz, Benito Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3362 - 3365
Route3
- 123-75-1
- 79-11-8
- ~%
- In-stock
  
  20266-00-6
References
- European Journal of Medicinal Chemistry, , vol. 41, # 8 p. 985 - 990

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 20.31
LogP 0.8476
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Key Words

2-Chloro-1-pyrrolidin-1-ylethanone sigma2-Chloro-1-pyrrolidin-1-ylethanone manufacturer2-Chloro-1-pyrrolidin-1-ylethanone price2-Chloro-1-pyrrolidin-1-ylethanone structure2-Chloro-1-pyrrolidin-1-ylethanone SDSbuy 2-Chloro-1-pyrrolidin-1-ylethanone2-Chloro-1-pyrrolidin-1-ylethanone supplier2-Chloro-1-pyrrolidin-1-ylethanone uses2-Chloro-1-pyrrolidin-1-ylethanone molecular weightprice of 2-Chloro-1-pyrrolidin-1-ylethanone2-Chloro-1-pyrrolidin-1-ylethanone chemical name formula of 2-Chloro-1-pyrrolidin-1-ylethanone

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-1-pyrrolidin-1-ylethanone

CAS No. 20266-00-6

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words