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Structure of 202197-73-7
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4-Oxo-3,4-dihydroquinazoline-7-carboxylic acid features a fused bicyclic core with a ketone at C4 and a carboxylic acid at C7, delivering high solubility and stability under standard bench conditions. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibition and exhibits favorable pharmacokinetic properties in preclinical models.
4-Oxo-3,4-dihydroquinazoline-7-carboxylic acid serves as a versatile scaffold in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard functional group transformations. Its stability and compatibility with common coupling reactions facilitate efficient derivatization for target-focused libraries. The carboxylic acid moiety supports direct amide formation and salt formation, enhancing solubility and handling. This compound functions as a key building block in the development of kinase inhibitors and other pharmacologically relevant architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: