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CS-W001157 4
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N-(2-Aminoethyl)methanesulfonamide hydrochloride

  • CAS No. 202197-61-3

  • Cat. No. CS-0067413
  • Molecule weight174.65
  • Purity≥97%
  • MDL No.MFCD11040488

*For research and further manufacturing use only, not for direct human use.

N-(2-Aminoethyl)methanesulfonamide hydrochloride|CS-0067413

Structure of 202197-61-3

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General Information

  • CAS No. 202197-61-3
  • Cat. No. CS-0067413
  • Purity ≥97%
  • MDL No. MFCD11040488
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₁₁ClN₂O₂S
  • Molecular Weight 174.65
  • Synonym(s) None
  • SMILES CS(=O)(NCCN)=O.[H]Cl

Description

N-(2-Aminoethyl)methanesulfonamide hydrochloride features a primary amine and sulfonamide group separated by an ethylene linker, delivering enhanced solubility and stability under standard conditions. This bifunctional scaffold enables efficient conjugation in bioconjugation workflows and serves as a key building block for targeted therapeutics.

Application

N-(2-Aminoethyl)methanesulfonamide hydrochloride serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient conjugation via its primary amine and sulfonamide groups. The hydrochloride salt enhances solubility and stability in aqueous systems, facilitating use in peptide coupling, macrocyclization, and scaffold diversification. Its well-documented compatibility with standard amide bond formation and orthogonal protection strategies makes it a practical choice for synthesizing targeted therapeutics and bioactive heterocycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.19
  • LogP   -1.0839
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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