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CS-W001157 4
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Thiomorpholin-3-one

  • CAS No. 20196-21-8

  • Cat. No. CS-W019146
  • Purity≥97%
  • MDL No.MFCD00152870
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Thiomorpholin-3-one|CS-W019146

Structure of 20196-21-8

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Description

Thiomorpholin-3-one offers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry. This bench-stable core integrates readily into bioactive molecules, providing enhanced metabolic stability and favorable binding interactions in target-directed drug discovery.

Application

Thiomorpholin-3-one serves as a versatile heterocyclic building block in medicinal chemistry, offering a stable, electron-deficient scaffold with a reactive thione functionality. It enables efficient derivatization via nucleophilic substitution and functions as a key motif in the synthesis of bioactive molecules, particularly within kinase inhibitors and antimicrobial agents. Its bench-stable nature and compatibility with standard coupling protocols facilitate straightforward incorporation into complex molecular architectures.

General Information

  • CAS No. 20196-21-8
  • Cat. No. CS-W019146
  • Purity ≥97%
  • MDL No. MFCD00152870
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NOS
  • Molecular Weight 117.17
  • Synonym(s) THIOMORPHOLINONE
  • SMILES O=C1NCCSC1

Computational Chemistry Data

  • TPSA   29.1
  • LogP   -0.1506
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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