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CS-W001157 4
Total: USD 88.00

Thiomorpholin-3-one

  • CAS No. 20196-21-8

  • Cat. No. CS-W019146
  • Molecule weight117.17
  • Purity≥97%
  • MDL No.MFCD00152870

*For research and further manufacturing use only, not for direct human use.

Thiomorpholin-3-one|CS-W019146

Structure of 20196-21-8

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General Information

  • CAS No. 20196-21-8
  • Cat. No. CS-W019146
  • Purity ≥97%
  • MDL No. MFCD00152870
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NOS
  • Molecular Weight 117.17
  • Synonym(s) THIOMORPHOLINONE
  • SMILES O=C1NCCSC1

Description

Thiomorpholin-3-one offers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry. This bench-stable core integrates readily into bioactive molecules, providing enhanced metabolic stability and favorable binding interactions in target-directed drug discovery.

Application

Thiomorpholin-3-one serves as a versatile heterocyclic building block in medicinal chemistry, offering a stable, electron-deficient scaffold with a reactive thione functionality. It enables efficient derivatization via nucleophilic substitution and functions as a key motif in the synthesis of bioactive molecules, particularly within kinase inhibitors and antimicrobial agents. Its bench-stable nature and compatibility with standard coupling protocols facilitate straightforward incorporation into complex molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   -0.1506
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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