Fmoc-D-Pen(Trt)-OH

Name: Fmoc-D-Pen(Trt)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 201532-01-6
Cat. No. CS-0101010
Purity≥95%
MDL No.MFCD00237389

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 201532-01-6

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Description

Fmoc-D-Pen(Trt)-OH is a protected D-phenylalanine derivative featuring a trifluoromethylcarbamoyl (Trt) group on the side chain, enabling orthogonal protection in peptide synthesis. This configuration supports efficient incorporation into challenging sequences where steric and electronic control are critical. The Fmoc moiety facilitates solution-phase and solid-phase coupling under standard conditions.

Application

Fmoc-D-Pen(Trt)-OH serves as a valuable building block for the solid-phase synthesis of peptides containing D-phenylalanine and protected D-penicillamine residues. The Trt (trityl) group provides orthogonal protection for the thiol functionality, enabling selective deprotection during chain assembly. This derivative exhibits excellent bench stability, facilitates efficient coupling reactions, and supports high-purity peptide synthesis through straightforward purification by acid-base extraction or chromatography.

General Information

CAS No. 201532-01-6
Cat. No. CS-0101010
Purity ≥95%
MDL No. MFCD00237389
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₉H₃₅NO₄S
Molecular Weight 613.76
Synonym(s) None
SMILES O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](C(O)=O)C(C)(C)SC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6

Computational Chemistry Data

TPSA 75.63
LogP 8.4822
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 10

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Fmoc

Life Science Amino Acids and their Derivatives Cysteine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-D-Pen(Trt)-OH

CAS No. 201532-01-6

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