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CS-W001157 4
Total: USD 88.00

3-Methyl-1H-indazol-6-ol

  • CAS No. 201286-99-9

  • Cat. No. CS-W006810
  • Purity≥95%
  • MDL No.MFCD08692367

*For research and further manufacturing use only, not for direct human use.

3-Methyl-1H-indazol-6-ol|CS-W006810

Structure of 201286-99-9

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General Information

  • CAS No. 201286-99-9
  • Cat. No. CS-W006810
  • Purity ≥95%
  • MDL No. MFCD08692367
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂O
  • Molecular Weight 148.16
  • Synonym(s) 3-Methyl-1H-indazol-6-ol
  • SMILES OC1=CC2=C(C=C1)C(C)=NN2

Description

6-Hydroxy-3-methylindazole delivers a bioactive scaffold featuring a phenolic hydroxyl group and methyl substituent on the indazole core. This combination enhances solubility and metabolic stability, enabling direct incorporation into kinase inhibitor and receptor modulator libraries under standard conditions.

Application

6-Hydroxy-3-methylindazole serves as a versatile building block for medicinal chemistry, enabling direct incorporation into bioactive heterocycles due to its ortho-hydroxyl and methyl-substituted indazole core. The phenolic hydroxyl group facilitates derivatization via etherification or esterification, while the indazole scaffold provides metabolic stability and hydrogen-bonding capacity. Bench-stable and readily purified by recrystallization, it functions efficiently in standard coupling and functionalization workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   1.57692
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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