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CS-W001157 4
Total: USD 88.00

4,6-Dibromodibenzofuran

  • CAS No. 201138-91-2

  • Cat. No. CS-0135838
  • Purity≥98%
  • MDL No.MFCD00185686

*For research and further manufacturing use only, not for direct human use.

4,6-Dibromodibenzofuran|CS-0135838

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General Information

  • CAS No. 201138-91-2
  • Cat. No. CS-0135838
  • Purity ≥98%
  • MDL No. MFCD00185686
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₆Br₂O
  • Molecular Weight 325.98
  • Synonym(s) Dibenzofuran, 4,6-dibromo-
  • SMILES BrC1=C(OC2=C(Br)C=CC=C23)C3=CC=C1

Description

4,6-Dibromodibenzofuran features a rigid, planar polycyclic framework with bromine substituents at the 4 and 6 positions, enabling selective coupling in cross-coupling reactions. This electron-deficient scaffold facilitates efficient palladium-catalyzed transformations, offering high stability under standard reaction conditions.

Application

4,6-Dibromodibenzofuran serves as a valuable building block for the synthesis of polycyclic aromatic systems and functionalized heterocycles. The dibromo substitution pattern enables efficient palladium-catalyzed cross-coupling reactions, facilitating the construction of complex biaryl architectures with high regiocontrol. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for iterative synthetic workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Schwartz, Elaine Benaksas; Knobler, Carolyn B.; Cram, Donald J. Journal of the American Chemical Society, 1992 , vol. 114, # 27 p. 10775 - 10784
  • Route2

    References

    • Evans, Catherine S.; Dellinger, Barry Environmental Science and Technology, 2005 , vol. 39, # 7 p. 2128 - 2134

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319-H413
Precautionary Statements : P264-P270-P273-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   13.14
  • LogP   5.111
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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