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CS-W001157 4
Total: USD 88.00

2-(4-Chlorophenyl)acetamide

  • CAS No. 20101-92-2

  • Cat. No. CS-0151382
  • Purity≥98%
  • MDL No.MFCD02380705

*For research and further manufacturing use only, not for direct human use.

2-(4-Chlorophenyl)acetamide|CS-0151382

Structure of 20101-92-2

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General Information

  • CAS No. 20101-92-2
  • Cat. No. CS-0151382
  • Purity ≥98%
  • MDL No. MFCD02380705
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈ClNO
  • Molecular Weight 169.61
  • Synonym(s) None
  • SMILES ClC1=CC=C(CC(N)=O)C=C1

Description

2-(4-Chlorophenyl)acetamide is a bench-stable amide featuring a para-chlorinated phenyl ring linked to an acetyl group. This structure imparts enhanced lipophilicity and metabolic stability, enabling efficient integration into pharmaceutical intermediates and bioactive molecule scaffolds under standard conditions.

Application

2-(4-Chlorophenyl)acetamide serves as a versatile building block in medicinal chemistry, enabling the construction of aryl-substituted amides and heterocyclic scaffolds. Its bench-stable nature and tolerance to common reaction conditions facilitate straightforward functionalization at the amide nitrogen or aromatic ring. Widely employed in API synthesis, it functions as a key intermediate in the development of bioactive molecules, particularly those requiring halogenated phenyl motifs for target engagement.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   1.3678
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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