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CS-W001157 4
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N-6-Methyl-2-deoxyadenosine

  • CAS No. 2002-35-9

  • Cat. No. CS-W012441
  • Purity≥95%
  • MDL No.MFCD00055999

*For research and further manufacturing use only, not for direct human use.

N-6-Methyl-2-deoxyadenosine|CS-W012441

Structure of 2002-35-9

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General Information

  • CAS No. 2002-35-9
  • Cat. No. CS-W012441
  • Purity ≥95%
  • MDL No. MFCD00055999
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₅N₅O₃
  • Molecular Weight 265.27
  • Synonym(s) m6dA
  • SMILES OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN=C3NC)=C3N=C2)O1

Application

N6-Methyl-2′-deoxyadenosine (CAS 2002-35-9) serves as a critical reference standard for quantifying modified nucleobases in genomic DNA using UHPLC-QQQ-MS/MS, enabling precise detection of epigenetic markers. It also stimulates erythroid progenitor cell proliferation. Researchers leverage this property to explore hematopoietic differentiation pathways and assess methylation impacts on cellular development.

Synthesis

  • Route1
    • null|null
      74873-17-9
    • ~78%
    • In-stock
      N-6-Methyl-2-deoxyadenosine|CS-W012441
      2002-35-9

    References

    • Helvetica Chimica Acta, , vol. 69, p. 1034 - 1040
  • Route2

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2787 - 2792
  • Route3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1327 - 1330

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   105.32
  • LogP   -0.4913
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   3

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