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CS-W001157 4
Total: USD 88.00

4,6-Difluoroindole

  • CAS No. 199526-97-1

  • Cat. No. CS-W018080
  • Purity≥98%
  • MDL No.MFCD01075213

*For research and further manufacturing use only, not for direct human use.

4,6-Difluoroindole|CS-W018080

Structure of 199526-97-1

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General Information

  • CAS No. 199526-97-1
  • Cat. No. CS-W018080
  • Purity ≥98%
  • MDL No. MFCD01075213
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅F₂N
  • Molecular Weight 153.13
  • Synonym(s) 4,6-difluoro-1H-indole
  • SMILES FC1=CC2=C(C(F)=C1)C=CN2

Description

Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Synthesis

  • Route1

    References

    • Bozilovic, Jelena; Engels, Joachim W. Nucleosides, Nucleotides and Nucleic Acids, 2007 , vol. 26, # 8-9 p. 869 - 871
  • Route2
    • Methyl 4,6-difluoro-1H-indole-2-carboxylate|CS-0094060
      394222-99-2
    • ~%
    • In-stock
      4,6-Difluoroindole|CS-W018080
      199526-97-1

    References

    • Canadian Journal of Chemistry, , vol. 85, # 4 p. 283 - 292
  • Route3

    References

    • Canadian Journal of Chemistry, , vol. 85, # 4 p. 283 - 292

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   2.4461
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   0

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