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CS-W001157 4
Total: USD 88.00

4-Chlorobenzo[d]thiazol-2-amine

  • CAS No. 19952-47-7

  • Cat. No. CS-W019581
  • Purity≥98%
  • MDL No.MFCD00005791

*For research and further manufacturing use only, not for direct human use.

4-Chlorobenzo[d]thiazol-2-amine|CS-W019581

Structure of 19952-47-7

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General Information

  • CAS No. 19952-47-7
  • Cat. No. CS-W019581
  • Purity ≥98%
  • MDL No. MFCD00005791
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅ClN₂S
  • Molecular Weight 184.65
  • Synonym(s) 4-chloro-1,3-benzothiazol-2-ylamine
  • SMILES C1=CC=C(C2=C1SC(=N2)N)Cl

Description

2-Amino-4-chlorobenzothiazole undergoes condensation reaction with 4-acetamidobenzaldehyde to form tridentate Schiff base.

Synthesis

  • Route1

    References

    • Claude, Saturnin; Tabacchi, Raffaele; Duc, Laurent; Fuchs, Rudolf; Boosen, Karl-Josef Helvetica Chimica Acta, 1980 , vol. 63, # 3 p. 682 - 692
  • Route2
    • N-(3-Chlorophenyl)thiourea|CS-0116703
      4947-89-1
    • ~80%
    • In-stock
      4-Chlorobenzo[d]thiazol-2-amine|CS-W019581
      19952-47-7

    References

    • PTC THERAPEUTICS, INC.; F. HOFFMANN-LA ROCHE AG; WOLL, Matthew G.; CHEN, Guangming; CHOI, Soongyu; DAKKA, Amal; HUANG, Song; KARP, Gary Mitchell; LEE, Chang-Sun; LI, Chunshi; NARASIMHAN, Jana; NARYSHKIN, Nikolai; PAUSHKIN, Sergey; QI, Hongyan; TURPOFF, Anthony A.; WEETALL, Marla L.; WELCH, Ellen; YANG, Tianle; ZHANG, Nanjing; ZHANG, Xiaoyan; ZHAO, Xin; PINARD, Emmanuel; RATNI, Hasane Patent: WO2013/101974 A1, 2013 ; Location in patent: Paragraph 00586; 00587 ;
  • Route3
    • null|null
      333-20-0
    • null|null
      95-51-2
    • ~10%
    • In-stock
      4-Chlorobenzo[d]thiazol-2-amine|CS-W019581
      19952-47-7

    References

    • Telvekar, Vikas N.; Bachhav, Harshal M.; Bairwa, Vinod Kumar Synlett, 2012 , vol. 23, # 15 p. 2219 - 2222

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.5319
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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