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CS-W001157 4
Total: USD 88.00

1-Isocyano-4-nitrobenzene

  • CAS No. 1984-23-2

  • Cat. No. CS-0265710
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-Isocyano-4-nitrobenzene|CS-0265710

Structure of 1984-23-2

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General Information

  • CAS No. 1984-23-2
  • Cat. No. CS-0265710
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄N₂O₂
  • Molecular Weight 148.12
  • Synonym(s) None
  • SMILES [C-]#[N+]C1=CC=C(C=C1)[N+](=O)[O-]

Description

1-Isocyano-4-nitrobenzene features a para-nitro group flanking a highly reactive isocyanide moiety, enabling efficient coupling in transition-metal-catalyzed transformations. This electron-deficient aryl isocyanide delivers robust performance in C–C and C–heteroatom bond formation under standard conditions.

Application

1-Isocyano-4-nitrobenzene serves as a versatile building block in transition-metal-catalyzed couplings and heterocycle synthesis, enabling efficient access to functionalized aromatic scaffolds. Its dual reactive handle—orthogonal isonitrile and nitro groups—facilitates sequential transformations with high chemoselectivity. The compound exhibits excellent bench stability and compatibility with common reaction conditions, simplifying purification and integration into multi-step synthetic sequences.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H334
Precautionary Statements : P261-P264-P270-P271-P280-P285-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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