2-Amino-5-acetylpyridine

Name: 2-Amino-5-acetylpyridine
Brand: ChemScene
Availability: InStock
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CAS No. 19828-20-7
Cat. No. CS-0044041
Purity≥95%
MDL No.MFCD09038484

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 19828-20-7

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Description

2-Amino-5-acetylpyridine features a pyridine core functionalized with an amino group at the 2-position and an acetyl moiety at the 5-position, delivering a versatile scaffold for medicinal chemistry. The electron-donating amino group enhances reactivity at the ring, while the acetyl substituent provides a handle for derivatization. This compound exhibits favorable solubility and stability under standard bench conditions, enabling straightforward integration into synthetic sequences.

Application

2-Amino-5-acetylpyridine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based pharmacophores. Its amino and acetyl groups offer orthogonal reactivity for Suzuki couplings, amidations, and electrophilic substitutions, facilitating the construction of complex heterocyclic scaffolds. The compound exhibits good bench stability and ease of purification, making it well-suited for high-throughput synthesis and process development workflows.

General Information

CAS No. 19828-20-7
Cat. No. CS-0044041
Purity ≥95%
MDL No. MFCD09038484
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈N₂O
Molecular Weight 136.15
Synonym(s) 5-ACETO-2-AMINOPYRIDINE
SMILES CC(=O)C1=CC=C(N)N=C1

Computational Chemistry Data

TPSA 55.98
LogP 0.8664
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Amino-5-acetylpyridine

CAS No. 19828-20-7

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