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CS-W001157 4
Total: USD 88.00

2-Amino-3-methoxypropanoic acid

  • CAS No. 19794-53-7

  • Cat. No. CS-W013587
  • Purity≥98%
  • MDL No.MFCD00037773

*For research and further manufacturing use only, not for direct human use.

2-Amino-3-methoxypropanoic acid|CS-W013587

Structure of 19794-53-7

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General Information

  • CAS No. 19794-53-7
  • Cat. No. CS-W013587
  • Purity ≥98%
  • MDL No. MFCD00037773
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉NO₃
  • Molecular Weight 119.12
  • Synonym(s) None
  • SMILES COCC(N)C(O)=O

Description

2-Amino-3-methoxypropanoic acid features a polar methoxy group flanking a chiral α-amino carboxylic acid scaffold, enhancing solubility and metabolic stability. This configuration supports its use in peptide conjugation and bioactive molecule synthesis under standard conditions.

Application

2-Amino-3-methoxypropanoic acid serves as a valuable chiral building block for peptide and heterocyclic synthesis, offering orthogonal reactivity between its amino and carboxylic acid functionalities. The methoxy group enhances solubility and provides a handle for further derivatization. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient incorporation into complex molecular architectures, including β-amino acid-containing scaffolds relevant to medicinal chemistry.

Synthesis

  • Route1

    References

    • Journal of Agricultural and Food Chemistry, , vol. 43, # 4 p. 867 - 871
  • Route2
    • 2-Acetamido-3-methoxypropanoic acid|CS-0233001
      98632-99-6
    • ~%
    • In-stock
      2-Amino-3-methoxypropanoic acid|CS-W013587
      19794-53-7

    References

    • Chemical Research in Toxicology, , vol. 11, # 7 p. 800 - 809
  • Route3
    • 2-Chloro-3-methoxypropionic acid|CS-W016486
      2544-05-0
    • ~%
    • In-stock
      2-Amino-3-methoxypropanoic acid|CS-W013587
      19794-53-7

    References

    • Tetrahedron, , vol. 17, p. 69 - 77

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   -0.9553
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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