Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromofuran-3-carboxylic acid

  • CAS No. 197846-05-2

  • Cat. No. CS-0029968
  • Purity≥97%
  • MDL No.MFCD09702417

*For research and further manufacturing use only, not for direct human use.

2-Bromofuran-3-carboxylic acid|CS-0029968

Structure of 197846-05-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 197846-05-2
  • Cat. No. CS-0029968
  • Purity ≥97%
  • MDL No. MFCD09702417
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrO₃
  • Molecular Weight 190.98
  • Synonym(s) 2-Bromo-3-Furoic Acid
  • SMILES O=C(C1=C(Br)OC=C1)O

Description

2-Bromofuran-3-carboxylic acid features a brominated furan ring fused to a carboxylic acid group, enabling direct functionalization in heterocyclic synthesis. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and agrochemical building blocks under standard conditions. The pendant acid facilitates derivatization via amide or ester formation, while the bromine serves as a handle for palladium-catalyzed cross-coupling reactions. Bench-stable and moisture-tolerant, it streamlines access to complex bioactive architectures.

Application

2-Bromofuran-3-carboxylic acid serves as a versatile building block for the synthesis of brominated heterocycles and pharmaceutical intermediates. Its functionality enables direct coupling reactions, including Suzuki-Miyaura and Stille transformations, due to the stable bromo substituent. The carboxylic acid group facilitates derivatization via esterification or amidation, enhancing solubility and reactivity in synthetic sequences. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses requiring orthogonal functional group handling.

Synthesis

  • Route1
    • null|null
      1710-13-0
    • ~%
    • In-stock
      2-Bromofuran-3-carboxylic acid|CS-0029968
      197846-05-2

    References

    • Journal of the American Chemical Society, , vol. 55, p. 2903,2908
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 40, # 23 p. 3804 - 3819

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.44
  • LogP   1.7403
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromofuran-3-carboxylic acid sigma2-Bromofuran-3-carboxylic acid manufacturer2-Bromofuran-3-carboxylic acid price2-Bromofuran-3-carboxylic acid structure2-Bromofuran-3-carboxylic acid SDSbuy 2-Bromofuran-3-carboxylic acid2-Bromofuran-3-carboxylic acid supplier2-Bromofuran-3-carboxylic acid uses2-Bromofuran-3-carboxylic acid molecular weightprice of 2-Bromofuran-3-carboxylic acid2-Bromofuran-3-carboxylic acid chemical name formula of 2-Bromofuran-3-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label