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Structure of 197792-52-2
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tert-Butyl 2-(3-bromophenyl)acetate features a brominated phenyl group attached to a benzylic acetate, enabling direct functionalization in cross-coupling reactions. The tert-butyl ester provides enhanced stability and ease of handling under standard conditions. This compound serves as a key intermediate in the synthesis of bioactive arylated molecules.
tert-Butyl 2-(3-bromophenyl)acetate serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromoaryl functionality. The tert-butyl ester group offers excellent bench stability and can be selectively removed under mild acidic conditions. Its compatibility with a range of reaction conditions facilitates efficient construction of biaryl scaffolds and functionalized heterocycles common in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: