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CS-W001157 4
Total: USD 88.00

1,3-Dibromo-5-iodobenzene

  • CAS No. 19752-57-9

  • Cat. No. CS-W006211
  • Purity≥96%
  • MDL No.MFCD07778996

*For research and further manufacturing use only, not for direct human use.

1,3-Dibromo-5-iodobenzene|CS-W006211

Structure of 19752-57-9

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General Information

  • CAS No. 19752-57-9
  • Cat. No. CS-W006211
  • Purity ≥96%
  • MDL No. MFCD07778996
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Br₂I
  • Molecular Weight 361.80
  • Synonym(s) 3,5-Dibromophenyl iodide
  • SMILES IC1=CC(Br)=CC(Br)=C1

Description

1,3-Dibromo-5-iodobenzene features a uniquely halogenated aromatic core with bromine and iodine substituents positioned at meta and para relative to one another. This electron-deficient scaffold enables direct coupling in cross-coupling reactions, offering high functional group tolerance and stability under standard conditions. The strategic placement of heavy halogens facilitates sequential transformations in synthetic sequences.

Application

1,3-Dibromo-5-iodobenzene serves as a versatile halogenated aromatic building block for palladium-catalyzed cross-coupling reactions. Its orthogonal halogen reactivity enables sequential functionalization, with bromine and iodine sites participating in distinct coupling events under selective catalytic conditions. The compound exhibits excellent bench stability and facilitates efficient synthesis of complex biaryl architectures, particularly in the construction of substituted heterocycles and pharmaceutical scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.8162
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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